Omeprazole enteric micro pill preparation material choice
Omeprazole pedantic acid volatile, the choice of complementary makings is crucial, the following by omeprazole micro pill related personnel to make a brief introduction:
Pellet accessories: aqueous solution, acid condition and light will cause decomposition of omeprazole, commonly used materials such as, lactose, all can lead to change color in pelletizing process.
Stable excipients: mannitol.
Coating and auxiliary material
Dilute acid resin commonly used enteric coating material, hydroxypropyl methyl cellulose phthalate acid polymer compound, is not directly to coating of omeprazole micro pill, omeprazole has the stable performance, so the selection as enteric coating isolation layer in front of the packaging material.
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