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Rabeprazole azole drug interactions
source:Vitalpharms Company Ltd.    Release date:2017-12-6 13:35:17

For ray Bella azole drug interaction is what? The zhuhai rabeprazole azole sodium professionals to introduce:

Rabeprazole azole by cytochrome P450 (CYP450) metabolism of metabolic enzyme system. Healthy subjects study, rabeprazole azole sodium had no obvious clinical and the other by CYP450 system of metabolic drug interactions. Rabeprazole sodium azole can produce continuous to inhibit the action of the gastric acid secretion.

Due to rabeprazole azole sodium decreased acidity, therefore, related to the absorption and gastric pH drug interactions. Normal subjects, for example, if a day at the same time take ketone health zun and 20 mg rabeprazole sodium azole, can make the bioavailability of ketone health zun decreases about 30%; At the same time taking digoxin, can make the AUC of digoxin and Cmax value increased by 19% and 29% respectively.

As a result, patients at the same time taking the medication should be monitored when sodium to rabeprazole sodium. Rabeprazole sodium azole taken with antacids and while taking antacids take again after 1 hour, rabeprazole azole average concentration in plasma area under the curve fell by 8% and 8% respectively.

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